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U N I -f O K U S

• BioGeoChemie des Watts Auf Beschluss der Deutschen Forschungsgemeinschaft wird an der Universität Oldenburg für die Dauer von sechs Jahren eine Forschergruppe "BioGeoChemie des Watts" eingerichtet. In den ersten drei Jahren erhält die Gruppe fast sechs Millionen DM Förderung. Der Antrag wurde federführend vom Institut für Chemie und Biologie des Meeres (ICBM) vorbereitet. Beteiligt sind außer...

B I O C O M P U T a T I O N

We now know that approximately 30,000 to 40,000 genes effectively control and regulate the human body. The recent completion of a rough draft of the human genome and the complete sequence of Drosophila melanogaster, Caenorhabditis elegans, Mycobacterium tuberculosis, and numerous other sequencing projects provide a vast amount of genomic data for further refinement and analysis.1 These landmark...

I C O M M U N C a T I O N I

C O M P U T a T I O N a N D M U L T I P L I C I T Y O F E Q U I L I B R I A

C O M P U T a T I O N a L B I O L O G Y

33 T he prevailing method of determining the sequence of a long DNA segment is the shotgun sequencing approach, in which a random sampling of short fragment sequences is acquired and then assembled by a computer program to infer the sampled segment's sequence. In the early 1980s, such segments were typically on the order of 5,000 to 10,000 base pairs (5 to 10 kbp). By 1990, this method was sequ...